Chicken Penne with Creamy Mushroom White Wine Sauce
5 from 3 votes
Print Pin It!

Chicken Penne with Creamy Mushroom White Wine Sauce

Chicken penne with creamy mushroom white wine sauce is made in one pan for a quick and easy dinner ready in 30 minutes.Perfect for weeknight dinners!
Prep Time 5 minutes
Cook Time 25 minutes
Total Time 30 minutes
Servings 4
Calories 733kcal
AUTHOR Neli Howard | Delicious Meets Healthy


  • 1 lb chicken breasts, chopped
  • 1 medium onion, chopped
  • 3 cloves garlic
  • 12 oz sliced mushrooms
  • 8 oz Penne pasta
  • 1 1/2 cup heavy whipping cream
  • 1/2 cup white wine
  • salt and pepper
  • 2 cups baby spinach
  • 1/4 cup parmesan cheese


  • Season chicken with salt, freshly ground black pepper and garlic powder. Heat oil in a large skillet over medium-high heat. Cook chicken for about 5 minutes per side, or until no longer pink in center. Transfer to a plate.
  • Add chopped onion to the skillet, and cook for a couple of minutes until translucent, stirring occasionally. Add minced garlic, and cook, while stirring for 30 seconds. Transfer to the plate with chicken.
  • Add sliced mushrooms and stir. Season mushrooms with salt and pepper. Let cook for about 5 minutes, stirring occasionally. When mushrooms are tender and most juices have evaporated, transfer them to the plate with chicken.
  • Add Penne pasta to the skillet and 4 cups water. Cook according to package instructions for about 10 minutes. 
  • When pasta is cooked, add whipping cream, white wine and continue cooking for about 5 minutes stirring occasionally or until sauce reduces a bit and thickens.
  • Add chicken, onions, and mushrooms back to the skillet, and fresh baby spinach. Stir everything. Serve warm and sprinkle some parmesan cheese on top.


Nutrition Facts
Chicken Penne with Creamy Mushroom White Wine Sauce
Amount Per Serving
Calories 733 Calories from Fat 342
% Daily Value*
Fat 38g58%
Saturated Fat 22g110%
Cholesterol 199mg66%
Sodium 288mg12%
Potassium 1037mg30%
Carbohydrates 52g17%
Fiber 3g12%
Sugar 4g4%
Protein 39g78%
Vitamin A 2800IU56%
Vitamin C 10.6mg13%
Calcium 180mg18%
Iron 2.2mg12%
* Percent Daily Values are based on a 2000 calorie diet.
Course Main Course
Cuisine American
Keyword 30 Minutes, Comfort Food, Gluten Free, Healthy, One Pan, One Skillet
DID YOU MAKE THIS RECIPE?Share a pic on Instagram. Tag & follow @deliciousmeetshealthy or tag #deliciousmeetshealthy!